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Pierce Catalog

Human IL-6 (Interleukin-6) Antibodies

IL-6 antibody matched pair for ELISA, ELISPOT, neutralization, and more.

Thermo Scientific Pierce IL-6 monoclonal and polyclonal antibodies enable the measurement of human interleukin-6 (IL-6). The monoclonal matched pair has been used in traditional sandwich ELISA assays and quantitative antibody arrays. Polyclonal antibody P620 is a neutralizing antibody that has been used in a variety of applications, including ELISA, immunoblot, and immunohistochemistry.

Cat # Type Format Isotype Clone# Cross-Reactivity Applications
M620 Purified F, PF, CF Mouse IgG1 5IL6 Hu ELISA (ref2,8), WB
Matched Pair: Coat
M621B Biotin-labeled F, P, C Mouse IgG1 7IL6 Hu ELISA (ref.2,5,8), WB
Matched Pair: Detect
P620 Purified F, PF, CF Rabbit Polyclonal Hu ELISA (ref3,6,9,10,11)
Immunoblot (ref5)
IH: paraffin (ref7)
In vitro Neutralization (ref1,4), WB

Format Codes: F=frozen, L=lyophilized, C=carrier, CF=carrier-free, P=preservative, PF=preservative-free

See info-sheets (PDF) in the ordering information table below for additional product-specific information.

Related Interleukin-6 (IL-6) Products

参考文献

  1. Biffl, W.L., et al. (1996). Interleukin-6 stimulates neutrophil production of platelet-activating factor. J. Leukoc. Biol. 59: 569-574.
  2. Burke, S.M. et al. (2008). Human mast cell activation with virus-associated stimuli leads to the selective Chemotaxis of natural killer cells by a CXCL8-dependent mechanism. Blood. 111, 5467-5476.
  3. Eckmann, L., et al. (1995). Entamoeba histolytica trophozoites induce an inflammatroy cytokine response by cultured human cells through the panacrine action of cytolytically released interleukin-1 alpha. J. Clin. Invest. 96, 1269-1279.
  4. Gomez-Guerrero, C., et al. (1994). Soluble IgA and IgG aggregates are catabolized by cultured rat mesangial cells and induce production of TNF-alpha and IL-6, and proliferation. J. Immunol. 153, 5247-5255.
  5. Hsiao, Y., et al. (2004). Tumor-infiltrating lymphocyte secretion of IL-6 antagonizes tumor-derived TGF-β1 and restores the lymphokine-activated killing activity. J. Immunol. 172, 1508-1514.
  6. Jung, H.C., et al. (1995). A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J. Clin. Invest. 95, 55-65.
  7. Marenda, S. A., et al. (1995). Localization of cytokines in cholesteatoma tissue. Otolaryngol. Head Neck Surg. 112, 359-368.
  8. May, L.T., et al. (1994). Sustained high levels of circulating chaperoned interleukin-6 after active specific cancer immunotherapy. Blood. 84, 1887-1895.
  9. Modur, V., et al. (1997). Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha. J. Clin. Invest. 100, 2752-2756.
  10. Rasmussen, S.J., et al. (1997). Secretion of proimflammatory cytokines by epithelial cells in response to chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis. J. Clin. Invest. 99, 77-87.
  11. Tapping, R.I., et al. (1999). Membrane-anchored forms of lipopolysaccharide (LPS)-binding protein do not mediate cellular responses to LPS independently of CD14. J. Immunol. 162, 5483-5489.
製品情報
Cat # 製　品　名 容 量 価 格 MSDS
M620 Human IL-6 MAb (clone 5IL6) 500 µg ¥63,000  
M621B Human IL-6 Biotinylated MAb (clone 7IL6) 250 µg ¥63,000 BID-P270
P620 Human IL-6 PAb 1mg ¥53,000